Dr. Darren Freed is a cardiac surgeon clinician-scientist with an interest in heart and lung failure and novel techniques to treat these conditions. His primary clinical interests are in cardiothoracic transplantation and mechanical circulatory assistance as well as less invasive cardiac surgery. His primary research interests are in ex-vivo organ perfusion, heart transplantation, mechanical circulatory support and the biological basis of myocardial fibrosis. He obtained his MD from the University of Alberta in 1998 and completed his cardiac surgical training at the University of Manitoba where he also obtained a Ph.D in Physiology in 2004. In 2007 he completed a Clinical Fellowship in Cardiothoracic Transplantation and Ventricular Assist Devices at Papworth Hospital in Cambridge, United Kingdom. He is currently an Associate Professor, Division of Cardiac Surgery, Department of Surgery, with cross appointments in the Departments of Physiology and Biomedical Engineering. He is the Director of Research for the Alberta Transplant Institute.
Nels is a Physicist who has 16 years experience in software development, firmware, and electrical engineering in Arizona. Starting with Testing and Requirements gathering at Molecular Imaging, he began Firmware Engineering by finding and fixing a bug in the Atomic Force Microscope controller firmware. Nels reviewed the hardware, finding and fixing electrical engineering bugs. He added software development to his firmware expertise, and then learned project management skills. Nels remained with the company following its acquisition by Agilent Technologies and became responsible for some AFM hardware before leaving Agilent and Arizona in July 2014, joining Darren Freed in founding Tevosol, Inc. in January 2015.
David graduated with his JD/MBA degree from the University of Toronto in 2001 and was called to the bar in 2002. In addition to the practice of law, David has co-founded and operated a successful software business and is active in federal politics. The ability to listen, absorb and synthesize facts and information and to break down complex issues to their core components is central to David’s approach to legal issues. He is known amongst his peers and clients for bringing novel approaches to difficult issues and reframing issues to create outside-the-box solutions and opportunities. In addition to business and the practice of law, David volunteers with and supports various non-profit and charitable organizations.
Dr. Jayan Nagendran is a cardiac surgeon clinician-scientist with an interest in end-stage lung disease and lung transplantation. The focus of his lab and clinical research is on the development and advancement of ex-vivo lung perfusion. He attended undergraduate and medical school at the University of Alberta, completing his MD in 2001. He joined the residency program in Cardiac Surgery at the University of Alberta from 2001-2009, and completed a Ph.D in Experimental Medicine during that time (2005-2008). After completing his cardiac surgical residency, Jayan sub-specialized in cardiothoracic transplantation surgery at Stanford University from 2009 to 2011. Dr. Nagendran’s pioneering roles in ex-vivo lung perfusion in Canada includes performing the first portable clinical ex-vivo lung perfusions in Canada. He created the second clinical ex-vivo lung perfusion program in Canada. He is the sole Canadian investigator of the largest international randomized controlled clinical trial examining the efficacy of ex-vivo lung perfusion compared to the standard of care (cold storage), the INSPIRE clinical trial. Dr. Nagendran is an Assistant Professor in the Department of Surgery and the Director of Research for the Division of Cardiac Surgery at the University of Alberta since 2011.
Carolyn has 8 years of management and technology commercialization experience, founding and operating her own business as well as managing small enterprises and technology start-ups. As a consultant with TEC Edmonton, she delivered projects involving market research and strategy, business planning and development, and financing and investments for technology industry clients. She was previously Director of Operations and Strategy for a health technology start-up, where she conducted strategic analyses, developed business plans, obtained funding, implemented project management processes, and secured strategic partnerships with distributors as well as the world’s leading software developer. She has advised on program expansions as well as assisted with designing new business development processes, including new methods, procedures and tools to ensure system wide alignment to business objectives. Carolyn holds a B.Sc. in Kinesiology from the University of Calgary and an MBA from the Haskayne School of Business.
Alexander Stickel B.Sc. P.Eng. graduated from the University of Alberta in 2004 with a B.Sc. in electrical engineering with a specialization in biomedical engineering. Prior to this, Alexander graduated in 2000 with a B.Sc. in Chemistry from The Kings University in Edmonton, Alberta, Canada. Alexander has over a decade of experience translating research equipment into commercial products. The bulk of which was in developing novel point of care medical diagnostic devices. From 2009 to 2011 Alexander participated in the Center for Point-of-Care Diagnostics initiatives sponsored by PATH, the University of Washington and the Bill and Melinda Gates foundation. This effort was to bring low-cost point-of-care medical devices to the global community. As the senior engineer at Tevosol, Alexander now joins immediately from one of the worlds foremost multinational technology developers.
Katie graduated from McGill University in 2014 with a BEng in Mechanical Engineering. In early 2015, Katie became the first engineering graduate student to join Dr. Darren Freed’s ex-vivo heart perfusion research team, a group that is developing the revolutionary “heart in a box” technology at the University of Alberta. With the guidance of a supervisory team with expertise in the Departments of Surgery, Physiology, Biomedical Engineering and Mechanical Engineering, Katie obtained an MSc in Biomedical Engineering in 2017. Her research focused on developing a compliant mock aorta for the ex-vivo heart perfusion system and experimentally determining its impact on cardiac performance. Katie joined the Tevosol team fresh out of her Masters ready to use her expertise to help bring this incredible technology to market.